Maŋnyɛ Mensima Clerk is a Career Philanthropist who has worked with international causes and also developed her own initiatives related to HIV prevention, sexual health promotion and traditional sexuality education in Africa.  In 2014, Maŋnyɛ Mensima conducted a 10-month tour of Africa, where she advocated for 'Sexual Health Practice' as a strategy, for improving the health status of African youth. Maŋnyɛ Mensima engaged with government officials, policy makers and traditional leaders, to promote sector-wide collaboration on delivery of sexual health services. Maŋnyɛ Mensima also engaged in awareness raising activities such as sexual health training sessions and condom distributions. In recognition of her efforts, Maŋnyɛ Mensima was appointed by UNAIDS Ghana to serve as UNAIDS Roving Goodwill Ambassador to Africa, in conjunction with her tour. As a Roving Ambassador, Maŋnyɛ Mensima promoted the Protect the Goal Campaign (PtG); part of a global initiative by UNAIDS and FIFA to prevent new HIV infections among young people.  During her tenure, Maŋnyɛ Mensima engaged with young people in schools, universities, youth organizations and football clubs, and encouraged countless young people, all across The Continent, to take the PtG Pledge and protect themselves from HIV.   

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Maŋnyɛ Mensima is also the Founder and President of The Kunim Foundation, a nonprofit organization dedicated to HIV and AIDS relief, and promoting sexual health among young people in Africa.  Through The Kunim Foundation, Maŋnyɛ has successfully introduced a sexual health training program within Dipo; the Dangme customary rite.  Through this program Maŋnyɛ Mensima has repackaged the ancient Dipo rite to now include modern sexual health information that is on par with school-based sexuality education programs; through her leadership, Dipo is now a platform for addressing emerging issues in womanhood and a force for improving the overall health and social status of GaDangme girls. Maŋnyɛ Mensima has also partnered with traditional councils and Royal Houses in Eswatini and South Africa, to extend The Kunim Foundation's programs to these countries.